DBCO-PEG4-VA-PBD, CAS 2241644-09-5

Product Description: DBCO-PEG4-VA-PBD is a agent-linker conjugate for ADC by using the antitumor antibiotic, Pyrrolobenzodiazepine (PBD), linked via DBCO-PEG4-VA[1]. DBCO-PEG4-VA-PBD is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

Applications: Cancer-programmed cell death

Formula: C80H87N9O16

References: [1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

CAS Number: 2241644-09-5

Molecular Weight: 1430.60

Compound Purity: 96.94

Research Area: Cancer

Solubility: DMSO : 120 mg/mL (ultrasonic)

Target: Drug-Linker Conjugates for ADC

• SKU: MEXHY-133433-10
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-133433-10
• Green Labware: No
• Package Unit: 10 mg
• Quantity Unit: STK