DBCO-PEG4-Val-Cit-PAB-MMAF, CAS 2244602-23-9

Product Description: DBCO-PEG4-Val-Cit-PAB-MMAF consists a cleavable 4 unit PEG ADC linker (DBCO-PEG4-Val-Cit-PAB) and a potent tubulin polymerization inhibitor (MMAF). DBCO-PEG4-Val-Cit-PAB-MMAF can be used in the synthesis of antibody-drug conjugates (ADCs)[1]. DBCO-PEG4-Val-Cit-PAB-MMAF is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

Applications: Cancer-programmed cell death

Formula: C88H126N12O20

References: [1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

CAS Number: 2244602-23-9

Molecular Weight: 1672.01

Compound Purity: 99.99

Research Area: Cancer

Solubility: DMSO : 250 mg/mL (ultrasonic)

Target: Drug-Linker Conjugates for ADC

• SKU: MEXHY-130990-25
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-130990-25
• Green Labware: No
• Package Unit: 25 mg
• Quantity Unit: STK