DBCO-Val-Cit-PABC-PNP

Product Description: DBCO-Val-Cit-PABC-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. DBCO-Val-Cit-PABC-PNP is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

Applications: Cancer-programmed cell death

Formula: C46H49N7O10

References: [1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

Molecular Weight: 859.92

Compound Purity: 96.54

Research Area: Cancer

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: ADC Linker

• SKU: MEXHY-130937-25
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-130937-25
• Green Labware: No
• Package Unit: 25 mg
• Quantity Unit: STK