DC44SMe, CAS 1354787-76-0

Product Description: DC44SMe, a phosphate proagent of cytotoxic DNA alkylator DC44, can be used in the synthesis of antibody-drug conjugate (ADC). DC44SMe exhibits IC50s of 2.0 nM, 2.8 nM, and 1.9 nM for Ramos, Namalwa, and HL60/s cancer cells, respectively. DC44SMe can be used for the targeted treatment of cancer[1].

Applications: Cancer-programmed cell death

Formula: C38H37ClN5O7PS2

References: [1]Zhao RY, et al. Synthesis and biological evaluation of antibody conjugates of phosphate prodrugs of cytotoxic DNA alkylators for the targeted treatment of cancer. J Med Chem. 2012 Jan 26;55(2):766-82.

CAS Number: 1354787-76-0

Molecular Weight: 806.29

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: ADC Cytotoxin

• SKU: MEXHY-135124-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-135124-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK