DM1-PEG4-DBCO

Product Description: DM1-(PEG)4-DBCO is a agent-linker conjugate composed of a potent microtubulin inhibitor DM1 and a linker DBCO-PEG4-Ahx to make antibody agent conjugate (ADC). Mertansine (DM1) is a microtubulin inhibitor and is an antibody-conjugatable maytansinoid that is developed to overcome systemic toxicity associated with maytansine and to enhance tumor-specific delivery. DM1-PEG4-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

Applications: Cancer-programmed cell death

Formula: C63H80ClN5O16

Molecular Weight: 1198.79

Compound Purity: 98.04

Research Area: Cancer

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: Drug-Linker Conjugates for ADC

• SKU: MEXHY-136261-5
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-136261-5
• Green Labware: No
• Package Unit: 5 mg
• Quantity Unit: STK