Product Description: Duostatin 5 is a cytotoxin designed based on dolastatin, can meet the requirement of serving as an effective cytotoxin in ADC, but has the advantages of fewer synthesis steps, easy operation, less difficulty in quality control and more stable chemical synthesis process[1]. Duostatin 5 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
Applications: Cancer-programmed cell death
Formula: C40H69N9O6
References: [1]Toxin for antibody drug conjugate and preparation method thereof. CN107857798B.
CAS Number: 2124210-34-8
Molecular Weight: 772.03
Compound Purity: 99.76
Research Area: Cancer
Solubility: DMSO : 125 mg/mL (ultrasonic)
Target: ADC Cytotoxin
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