Fmoc-8-amino-3,6-dioxaoctanoic acid, CAS 166108-71-0

Product Description: Fmoc-8-amino-3,6-dioxaoctanoic acid (Fmoc-NH-PEG2-CH2COOH) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-8-amino-3,6-dioxaoctanoic acid is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Applications: Cancer-programmed cell death

Formula: C21H23NO6

References: [1]Nakamura A, et al. Chemogenetic Control of Protein Anchoring to Endomembranes in Living Cells with Lipid-Tethered Small Molecules. Biochemistry. 2020 Jan 21;59(2):205-211.

CAS Number: 166108-71-0

Molecular Weight: 385.41

Compound Purity: 99.98

Research Area: Cancer

Solubility: DMSO : 25 mg/mL (ultrasonic;warming;heat to 60°C)

Target: ADC Linker;PROTAC Linkers

• SKU: MEXHY-W007713-1G
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-W007713-1G
• Green Labware: No
• Package Unit: 1 g
• Quantity Unit: STK