γ-Amanitin, CAS 21150-23-2

Product Description: γ-Amanitin an ADC cytotoxin and isolated from the mushroom. γ-Amanitin inhibits RNA polymerase II and disrupts synthesis of mRNA. γ-Amanitin shows similar effects to α-Amanitin and β-Amanitin. γ-Amanitin competitively binds to monoclonal antibody (mAb), with an IC50 of 163.1 ng/mL[1].

Applications: Cancer-programmed cell death

Formula: C39H54N10O13S

References: [1]He K, et al. Production of a broad-specificity monoclonal antibody and application as a receptor to detection amatoxins in mushroom. Biologicals. 2017 Sep;49:57-61.

CAS Number: 21150-23-2

Molecular Weight: 902.97

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: ADC Cytotoxin;DNA/RNA Synthesis

• SKU: MEXHY-131081-25
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-131081-25
• Green Labware: No
• Package Unit: 25mg
• Quantity Unit: STK