Gemtuzumab ozogamicin, CAS 220578-59-6

Product Description: Gemtuzumab ozogamicin is an antibody-drug conjugate (ADC) consisting of a humanized immunoglobulin (IgG4) antibody directed against CD33 that is conjugated to the cytotoxic drug Calicheamicin (HY-19609). Calicheamicin is a cytotoxic antibiotic. Gemtuzumab ozogamicin can be used for the research of acute myeloid leukemia (AML)[1][2].

Applications: Cancer-programmed cell death

Formula: N/A

References: [1]Baron J, et al. Gemtuzumab ozogamicin for the treatment of acute myeloid leukemia. Expert Rev Clin Pharmacol. 2018;11(6):549-559. /[2]Yi Liu, et al. CD33-directed immunotherapy with third-generation chimeric antigen receptor T cells and gemtuzumab ozogamicin in intact and CD33-edited acute myeloid leukemia and hematopoietic stem and progenitor cells. Int J Cancer. 2022 Apr 1;150(7):1141-1155.

CAS Number: 220578-59-6

Molecular Weight: 151000 (average)

Compound Purity: 98.00

Research Area: Cancer

Solubility: H2O

Target: Antibody-Drug Conjugates (ADCs);Apoptosis

• SKU: MEXHY-109539-100UG
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-109539-100UG
• Green Labware: No
• Package Unit: 100 μg
• Quantity Unit: STK