Gly-Gly-Phe-Gly-NH-O-CO-Exatecan (hydrochloride)

Product Description: Gly-Gly-Phe-Gly-NH-O-CO-Exatecan, as a drug-linker conjugate composed of linker Gly-Gly-Phe-Gly-NH-O-CO and Exatecan, can be used to prepare antibody conjugate drugs. Exatecan is a DNA topoisomerase I inhibitor that can be used in cancer research[1][2].

Applications: Cancer-programmed cell death

Formula: C42H46ClFN8O10

References: [1]Joto N, et al. DX-8951f, a water-soluble camptothecin analog, exhibits potent antitumor activity against a human lung cancer cell line and its SN-38-resistant variant. Int J Cancer. 1997;72(4):680-686./[2]Thomas A, et al. Antibody-drug conjugates for cancer therapy. Lancet Oncol. 2016;17(6):e254-e262.

Molecular Weight: 877.31

Compound Purity: 99.89

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Drug-Linker Conjugates for ADC;Topoisomerase

• SKU: MEXHY-13631F-10
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-13631F-10
• Green Labware: No
• Package Unit: 10 mg
• Quantity Unit: STK