H-Glu-OtBu, CAS 45120-30-7

Product Description: H-Glu-OtBu is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). H-Glu-OtBu is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[2

Applications: Cancer-programmed cell death

Formula: C9H17NO4

References: [1]Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985./[2]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017;16(5):315-337.

CAS Number: 45120-30-7

Molecular Weight: 203.24

Compound Purity: 98.0

Research Area: Cancer

Solubility: DMSO : 10 mg/mL (ultrasonic;warming;heat to 60°C)

Target: ADC Linker;PROTAC Linkers

• SKU: MEXHY-W018154-5G
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-W018154-5G
• Green Labware: No
• Package Unit: 5 g
• Quantity Unit: STK