Lys(MMT)-PAB-oxydiacetamide-PEG8-N3, CAS 1224601-12-0

Product Description: Lys(MMT)-PAB-oxydiacetamide-PEG8-N3 is a cleavable antibody agent conjugate linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Lys(MMT)-PAB-oxydiacetamide-PEG8-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.

Applications: Cancer-programmed cell death

Formula: C55H77N7O14

References: [1]Serengulam V. Govindan, et al. EFFICACY OF ANTI-HLA-DR ANTIBODY DRUG CONJUGATE IMMU-140 (hL243-CL2A-SN-38) IN HLA-DR POSITIVE CANCERS. Patent US20170360770.

CAS Number: 1224601-12-0

Molecular Weight: 1060.24

Compound Purity: 95.16

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: ADC Linker

• SKU: MEXHY-131157-250
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-131157-250
• Green Labware: No
• Package Unit: 250 mg
• Quantity Unit: STK