MAC glucuronide α-hydroxy lactone-linked SN-38, CAS 2246380-70-9

Product Description: MAC glucuronide α-hydroxy lactone-linked SN-38 (Topoisomerase I inhibitor) is a stabilized lactone MAC glucuronide α-hydroxy lactone-linked SN-38 agent linker. MAC glucuronide α-hydroxy lactone-linked SN-38 is cytotoxic across L540cy cells and Ramos cells with IC50 values of 99 and 105 ng/mL, respectively[1].

Applications: Cancer-programmed cell death

Formula: C50H54N6O20S

References: [1]Lau UY, et al. Lactone Stabilization is Not a Necessary Feature for Antibody Conjugates of Camptothecins. Mol Pharm. 2018 Sep 4;15(9):4063-4072.

CAS Number: 2246380-70-9

Molecular Weight: 1091.06

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Drug-Linker Conjugates for ADC

• SKU: MEXHY-128942-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-128942-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK