Maleimido-tri(ethylene glycol)-propionic acid, CAS 518044-40-1

Product Description: Maleimido-tri(ethylene glycol)-propionic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Maleimido-tri(ethylene glycol)-propionic acid is used for the preparation of neolymphostin-based ADC precursors for site-specific cysteine mutant trastuzumab-A114C conjugation[1]. Maleimido-tri(ethylene glycol)-propionic acid also can be used as a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Applications: Cancer-programmed cell death

Formula: C13H19NO7

References: [1]Zhou D,et al. Novel PIKK inhibitor antibody-drug conjugates: Synthesis and anti-tumor activity.Bioorg Med Chem Lett. 2019 Apr 1;29(7):943-947.

CAS Number: 518044-40-1

Molecular Weight: 301.29

Compound Purity: 99.14

Research Area: Cancer

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: ADC Linker;PROTAC Linkers

• SKU: MEXHY-130426-100
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-130426-100
• Green Labware: No
• Package Unit: 100 mg
• Quantity Unit: STK