Product Description: Mc-Leu-Gly-Arg is a cleavable ether linker for antibody-drug conjugates (ADC) design.
Applications: Cancer-programmed cell death
Formula: C21H34N6O6
References: [1]Zhang D, et al. Immolation of p-Aminobenzyl Ether Linker and Payload Potency and Stability Determine the Cell-Killing Activity of Antibody-Drug Conjugates with Phenol-Containing Payloads. Bioconjug Chem. 2018 Feb 21;29(2):267-274.