MC-Sq-Cit-PAB-Dolastatin10, CAS 1941168-65-5

Product Description: MC-Sq-Cit-PAB-Dolastatin10 is a agent-linker conjugate for ADC with potent antitumor activity by using Dolastatin10 (a tubulin polymerization inhibitor), linked via the ADC linker MC-Sq-Cit-PAB.

Applications: Cancer-programmed cell death

Formula: C70H105N12O12S

References: [1]Staben LR, et al. Targeted drug delivery through the traceless release of tertiary and heteroaryl amines from antibody-drug conjugates. Nat Chem. 2016 Dec;8(12):1112-1119./[2]FLYGARE, John A, et al. Quaternary amine compounds and antibody-drug conjugates thereof. WO2016090050A1.

CAS Number: 1941168-65-5

Molecular Weight: 1338.72

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Drug-Linker Conjugates for ADC

• SKU: MEXHY-128894-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-128894-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK