MC-VA-PABC-MMAE, CAS 1818864-51-5

Product Description: MC-VA-PABC-MMAE is a agent-linker conjugate for ADC. MC-VA-PABC-MMAE contains the ADCs linker (peptide MC-VA-PABC) and a potent tubulin polymerization inhibitor MMAE (HY-15162)[1][2].

Applications: Cancer-programmed cell death

Formula: C65H99N9O14

References: [1]Wang Y, et al. Development of applicable thiol-linked antibody-drug conjugates with improved stability and therapeutic index. Drug Deliv. 2022 Dec;29(1):754-766./[2]Cazzamalli S, et al. Linker stability influences the anti-tumor activity of acetazolamide-drug conjugates for the therapy of renal cell carcinoma. J Control Release. 2017 Jan 28;246:39-45.

CAS Number: 1818864-51-5

Molecular Weight: 1230.53

Compound Purity: 99.88

Research Area: Cancer

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: Drug-Linker Conjugates for ADC

• SKU: MEXHY-147239-5
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-147239-5
• Green Labware: No
• Package Unit: 5 mg
• Quantity Unit: STK