N,N-Bis(PEG2-alkyne)-N-amido-PEG2-thiol

N,N-Bis(PEG2-alkyne)-N-amido-PEG2-thiol
SKU
MEXHY-136130-0
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MedChemExpress

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Product Description: N,N-Bis(PEG2-alkyne)-N-amido-PEG2-thiol is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. N,N-Bis(PEG2-alkyne)-N-amido-PEG2-thiol is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Applications: Cancer-programmed cell death

Formula: C21H35NO7S

References: [1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

Molecular Weight: 445.57

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: ADC Linker
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SKU MEXHY-136130-0
Manufacturer MedChemExpress
Manufacturer SKU HY-136130-0
Green Labware No
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