N3-PEG4-amido-Lys(Fmoc)-acid

Product Description: N3-PEG4-amido-Lys(Fmoc)-acid is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. N3-PEG4-amido-Lys(Fmoc)-acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.

Applications: Cancer-programmed cell death

Formula: C32H43N5O9

References: [1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

Molecular Weight: 641.71

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: ADC Linker

• SKU: MEXHY-136058-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-136058-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK