PC Biotin-PEG3-azide, CAS 1937270-46-6

Product Description: PC Biotin-PEG3-azide is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. PC Biotin-PEG3-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.

Applications: Cancer-programmed cell death

Formula: C35H55N9O12S

References: [1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

CAS Number: 1937270-46-6

Molecular Weight: 825.93

Compound Purity: 99.25

Research Area: Cancer

Solubility: DMSO : 50 mg/mL (ultrasonic;warming;heat to 60°C)

Target: ADC Linker

• SKU: MEXHY-140132-1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-140132-1
• Green Labware: No
• Package Unit: 1 mg
• Quantity Unit: STK