PF-06380101, CAS 1436391-86-4

Product Description: PF-06380101 (Aur0101), an auristatin microtubule inhibitor, is a cytotoxic Dolastatin 10 analogue. PF-06380101 (Aur0101) shows excellent potencies in tumor cell proliferation assays and differential ADME properties when compared to other synthetic auristatin analogues that are used in the preparation of ADCs.

Applications: Cancer-programmed cell death

Formula: C39H62N6O6S

References: [1]Maderna A, et al. Discovery of cytotoxic dolastatin 10 analogues with N-terminal modifications. J Med Chem. 2014 Dec 26;57(24):10527-43.

CAS Number: 1436391-86-4

Molecular Weight: 743.01

Compound Purity: 99.47

Research Area: Cancer

Solubility: DMSO : ≥ 65 mg/mL

Target: ADC Cytotoxin;Microtubule/Tubulin

• SKU: MEXHY-12522-10
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-12522-10
• Green Labware: No
• Package Unit: 10 mg
• Quantity Unit: STK