Propargyl-O-C1-amido-PEG3-C2-NHS ester, CAS 2101206-78-2

Propargyl-O-C1-amido-PEG3-C2-NHS ester, CAS 2101206-78-2
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MEXHY-133583-0
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MedChemExpress

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Product Description: Propargyl-O-C1-amido-PEG3-C2-NHS ester is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Propargyl-O-C1-amido-PEG3-C2-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Applications: Cancer-programmed cell death

Formula: C18H26N2O9

References: [1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

CAS Number: 2101206-78-2

Molecular Weight: 414.41

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: ADC Linker
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SKU MEXHY-133583-0
Manufacturer MedChemExpress
Manufacturer SKU HY-133583-0
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