Propargyl-PEG2-amine, CAS 944561-44-8

Product Description: Propargyl-PEG2-amine is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Propargyl-PEG2-amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1][2]. Propargyl-PEG2-amine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Applications: Cancer-programmed cell death

Formula: C7H13NO2

References: [1]Changchun Wang, et al. A kind of antibody coupling matter and its construction method containing boron ester units polymer. CN108721642A./[2]Guangrong Zheng, et al. Bcl-2 proteins degraders for cancer treatment. WO2019144117A1.

CAS Number: 944561-44-8

Molecular Weight: 143.18

Compound Purity: 99.64

Research Area: Cancer

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: ADC Linker;PROTAC Linkers

• SKU: MEXHY-W051634-100
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-W051634-100
• Green Labware: No
• Package Unit: 100 mg
• Quantity Unit: STK