(Rac)-Lys-SMCC-DM1

Product Description: (Rac)-Lys-SMCC-DM1 ((Rac)-Lys-Nε-MCC-DM1) is the racemate of Lys-SMCC-DM1 (HY-101982). Lys-SMCC-DM1 is a linker-payload component that has the potential to inhibit tubulin polymerization. Lys-SMCC-DM1 is the active metabolite of T-DM1[1].

Applications: Cancer-programmed cell death

Formula: C53H75ClN6O15S

References: [1]Ogitani Y, et al. Bystander killing effect of DS-8201a, a novel anti-human epidermal growth factor receptor 2 antibody-drug conjugate, in tumors with human epidermal growth factor receptor 2 heterogeneity. Cancer Sci. 2016 Jul;107(7):1039-46.

Molecular Weight: 1103.71

Compound Purity: 98.18

Research Area: Cancer

Solubility: DMSO : 50 mg/mL (ultrasonic)

Target: Drug-Linker Conjugates for ADC

• SKU: MEXHY-101982A-1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-101982A-1
• Green Labware: No
• Package Unit: 1 mg
• Quantity Unit: STK