S-(1-Hydroxy-2-methylpropan-2-yl) methanesulfonothioate, CAS 2127875-65-2

Product Description: S-(1-Hydroxy-2-methylpropan-2-yl) methanesulfonothioate is a glutathione cleavable ADC linker used for the antibody-drug conjugates (ADCs) and refers to the Alkyl-Chain composition. S-(1-Hydroxy-2-methylpropan-2-yl) methanesulfonothioate is the linker portions of the molecules employed for mAb attachment purposes[1].

Applications: Cancer-programmed cell death

Formula: C5H12O3S2

References: [1]Pillow TH, et al. Antibody Conjugation of a Chimeric BET Degrader Enables in vivo Activity. ChemMedChem. 2019 Oct 31.

CAS Number: 2127875-65-2

Molecular Weight: 184.28

Compound Purity: 95.0

Research Area: Cancer

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: ADC Linker

• SKU: MEXHY-129942-250
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-129942-250
• Green Labware: No
• Package Unit: 250 mg
• Quantity Unit: STK