Seco-DUBA, CAS 1227961-59-2

Product Description: Seco-DUBA is a duocarmycin (DUBA) prodrug containing two hydroxyl groups, which can each be used for coupling to an antibody via a linker. Seco-DUBA can be used in the synthesis of antibody-drug conjugates (ADCs)[1].

Applications: Cancer-programmed cell death

Formula: C29H23ClN4O4

References: [1]Elgersma RC, et al. Design, Synthesis, and Evaluation of Linker-Duocarmycin Payloads: Toward Selection of HER2-Targeting Antibody-Drug Conjugate SYD985. Mol Pharm. 2015;12(6):1813-1835./[2]Platform Technologies in Drug Discovery and Validation

CAS Number: 1227961-59-2

Molecular Weight: 526.97

Compound Purity: 95.81

Research Area: Cancer; Inflammation/Immunology

Solubility: DMSO : 100 mg/mL (ultrasonic;warming;heat to 60°C)

Target: ADC Cytotoxin

• SKU: MEXHY-132180A-1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-132180A-1
• Green Labware: No
• Package Unit: 1 mg
• Quantity Unit: STK