Product Description: SMCC-DM1 (DM1-SMCC) is a agent-linker conjugate composed of a potent microtubule-disrupting agent DM1 and a linker SMCC to make antibody agent conjugate (ADC)[1].
Applications: Cancer-programmed cell death
Formula: C51H66ClN5O16S
References: [1]Shao S, et al. Site-specific and hydrophilic ADCs through disulfide-bridged linker and branched PEG. Bioorg Med Chem Lett. 2018 May 1;28(8):1363-1370.
CAS Number: 1228105-51-8
Molecular Weight: 1072.61
Compound Purity: 98.87
Research Area: Cancer
Solubility: DMSO : 16.67 mg/mL (ultrasonic;warming;heat to 80°C)