Sulfo-SPDB-DGN462

Product Description: Sulfo-SPDB-DGN462 is a agent-linker conjugate for ADC. Sulfo-SPDB-DGN462 consists a toxin DGN462 (HY-101150) conjugated to the cleavable Sulfo-SPDB linker. DGN462, a potent DNA-alkylating agent, shows anti-tumor activity, such as acute myeloid leukemia (AML).

Applications: Cancer-programmed cell death

Formula: C61H66N6O17S3

References: [1]Hicks SW, et al. The novel CD19-targeting antibody-drug conjugate huB4-DGN462 shows improved anti-tumor activity compared to SAR3419 in CD19-positive lymphoma and leukemia models. Haematologica. 2019 Aug;104(8):1633-1639.

Molecular Weight: 1251.40

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Drug-Linker Conjugates for ADC

• SKU: MEXHY-136291-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-136291-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK