sulfo-SPDB-DM4, CAS 1626359-59-8

Product Description: sulfo-SPDB-DM4 is a agent-linker conjugate for ADC by using the maytansinebased payload (DM4, an antitubulin agent) via the sulfo-SPDB linker.

Applications: Cancer-programmed cell death

Formula: C46H63ClN4O17S3

References: [1]Tang R, et al. P-gp activity is a critical resistance factor against AVE9633 and DM4 cytotoxicity in leukaemia cell lines, but not a major mechanism of chemoresistance in cells from acute myeloid leukaemia patients. BMC Cancer. 2009 Jun 23;9:199.

CAS Number: 1626359-59-8

Molecular Weight: 1075.66

Compound Purity: 99.97

Research Area: Cancer

Solubility: DMSO : 50 mg/mL (ultrasonic)

Target: Drug-Linker Conjugates for ADC

• SKU: MEXHY-101141-5
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-101141-5
• Green Labware: No
• Package Unit: 5 mg
• Quantity Unit: STK