Product Description: TAM470 is a novel cytolysin, inhibiting tubulin polymerization and microtubule depolymerization. TAM470 can be used in the synthesis of OMTX705 as payload molecule, OMTX705 is a novel FAP-targeting antibody-drug conjugates (ADCs) with antitumor activity[1].
Applications: Cancer-programmed cell death
Formula: C41H67N7O6S
References: [1]Fabre M, et al. OMTX705, a Novel FAP-Targeting ADC Demonstrates Activity in Chemotherapy and Pembrolizumab-Resistant Solid Tumor Models. Clin Cancer Res. 2020 Jul 1;26(13):3420-3430.
CAS Number: 1802498-63-0
Molecular Weight: 786.08
Compound Purity: 98.53
Research Area: Cancer
Solubility: DMSO : 100 mg/mL (ultrasonic)
Target: ADC Cytotoxin;Microtubule/Tubulin