Thalidomide-NH-PEG7, CAS 2641838-98-2

Product Description: Thalidomide-NH-PEG7 is a synthesized E3 ligase ligand-linker conjugate for ADC. Thalidomide-NH-PEG7 can be connected to the ligand for protein by a linker to form PROTAC iRucaparib-AP6, a highly specific PARP1 degrader[1].

Applications: Cancer-programmed cell death

Formula: C27H39N3O11

References: [1]Wang S, et al. Uncoupling of PARP1 trapping and inhibition using selective PARP1 degradation.Nat Chem Biol. 2019 Dec;15(12):1223-1231.

CAS Number: 2641838-98-2

Molecular Weight: 581.61

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Apoptosis;Autophagy;E3 Ligase Ligand-Linker Conjugates

• SKU: MEXHY-130648-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-130648-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK