Tubulysin A intermediate-1

Product Description: Tubulysin A intermediate-1 is an intermediate in the synthesis of the cytotoxic peptide Tubulysin A (HY-15995). Tubulysin A (TubA) is an antibiotic, anti-microtubule toxins, and apoptosis inducer isolated from myxobacteria. Tubulysin A has anti-angiogenic, anti-microtubule, anti-mitotic, and anti-proliferative activities. Tubulysin A arrests cells in the G2/M phase, effectively inhibits tubulin polymerization, and induces depolymerization of detached microtubules. Tubulysin A acts as an ADC cytotoxin (ADC Cytotoxin) to synthesize ADC[1].

Applications: Cancer-programmed cell death

Formula: C31H52N4O7S

Molecular Weight: 624.83

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Others

• SKU: MEXHY-400684-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-400684-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK