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ADC Related

ADC Related

The ADC, antibody-drug conjugate, a humanised or human monoclonal antibody with conjugated highly potent cytotoxic small molecules (payloads), is a novel therapeutic format with great potential for a paradigm shift in cancer chemotherapy. The three components of the ADC form a powerful oncolytic agent capable of delivering normally untolerated cytotoxins directly to cancer cells, which then internalise and release the cytotoxic drugs. Currently, two ADCs, Adcetris and Kadcyla, have received marketing authorisation and more than 40 others are in clinical development.

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  1. Ald-Ph-amido-PEG11-C2-NH2, CAS 1337889-01-6
    Ald-Ph-amido-PEG11-C2-NH2, CAS 1337889-01-6
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    Sku MEXHY-133546-0
    Manufact. SkuHY-133546-0
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  2. Mal-Ph-CONH-PEG4-​NHS ester, CAS 1263044-88-7
    Mal-Ph-CONH-PEG4-​NHS ester, CAS 1263044-88-7
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    Sku MEXHY-133545-250
    Manufact. SkuHY-133545-250
    Packaging Unit250 mg
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  3. Mal-Ph-CONH-PEG4-​NHS ester, CAS 1263044-88-7
    Mal-Ph-CONH-PEG4-​NHS ester, CAS 1263044-88-7
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    Sku MEXHY-133545-100
    Manufact. SkuHY-133545-100
    Packaging Unit100 mg
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  4. Mal-CO-PEG5-​NHS ester, CAS 1232769-29-7
    Mal-CO-PEG5-​NHS ester, CAS 1232769-29-7
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    Sku MEXHY-133544-0
    Manufact. SkuHY-133544-0
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  5. SPDP-sulfo, CAS 121115-30-8
    SPDP-sulfo, CAS 121115-30-8
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    Sku MEXHY-133543-0
    Manufact. SkuHY-133543-0
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  6. Dimethylamine-SPDB, CAS 1193111-73-7
    Dimethylamine-SPDB, CAS 1193111-73-7
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    Sku MEXHY-133542-0
    Manufact. SkuHY-133542-0
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  7. Maleimide-DOTA, CAS 1006711-90-5
    Maleimide-DOTA, CAS 1006711-90-5
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    Sku MEXHY-133540-50
    Manufact. SkuHY-133540-50
    Packaging Unit50 mg
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  8. Maleimide-DOTA, CAS 1006711-90-5
    Maleimide-DOTA, CAS 1006711-90-5
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    Sku MEXHY-133540-25
    Manufact. SkuHY-133540-25
    Packaging Unit25 mg
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  9. Maleimide-DOTA, CAS 1006711-90-5
    Maleimide-DOTA, CAS 1006711-90-5
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    Sku MEXHY-133540-100
    Manufact. SkuHY-133540-100
    Packaging Unit100 mg
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  10. Propargyl-C8-amido-PEG2-NHS ester, CAS 1006592-59-1
    Propargyl-C8-amido-PEG2-NHS ester, CAS 1006592-59-1
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    Sku MEXHY-133539-0
    Manufact. SkuHY-133539-0
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