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ADC Related

ADC Related

The ADC, antibody-drug conjugate, a humanised or human monoclonal antibody with conjugated highly potent cytotoxic small molecules (payloads), is a novel therapeutic format with great potential for a paradigm shift in cancer chemotherapy. The three components of the ADC form a powerful oncolytic agent capable of delivering normally untolerated cytotoxins directly to cancer cells, which then internalise and release the cytotoxic drugs. Currently, two ADCs, Adcetris and Kadcyla, have received marketing authorisation and more than 40 others are in clinical development.

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  1. m-PEG5-succinimidyl carbonate, CAS 1058691-00-1
    m-PEG5-succinimidyl carbonate, CAS 1058691-00-1
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    Sku MEXHY-130150-0
    Manufact. SkuHY-130150-0
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  2. Ald-CH2-PEG3-azide, CAS 1002342-83-7
    Ald-CH2-PEG3-azide, CAS 1002342-83-7
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    Sku MEXHY-130144-0
    Manufact. SkuHY-130144-0
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  3. N-Succinimidyloxycarbonylpropyl methanethiosulfonate, CAS 690632-55-4
    N-Succinimidyloxycarbonylpropyl methanethiosulfonate, CAS 690632-55-4
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    Sku MEXHY-130112-0
    Manufact. SkuHY-130112-0
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  4. DMAC-SPP, CAS 663599-10-8
    DMAC-SPP, CAS 663599-10-8
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    Sku MEXHY-130111-0
    Manufact. SkuHY-130111-0
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  5. Sulfo-DMAC-SPP, CAS 663599-11-9
    Sulfo-DMAC-SPP, CAS 663599-11-9
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    Sku MEXHY-130110-0
    Manufact. SkuHY-130110-0
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  6. N3-PEG4-C2-NHS ester, CAS 944251-24-5
    N3-PEG4-C2-NHS ester, CAS 944251-24-5
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    Sku MEXHY-130109-50
    Manufact. SkuHY-130109-50
    Packaging Unit50 mg
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  7. N3-PEG4-C2-NHS ester, CAS 944251-24-5
    N3-PEG4-C2-NHS ester, CAS 944251-24-5
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    Sku MEXHY-130109-25
    Manufact. SkuHY-130109-25
    Packaging Unit25 mg
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  8. N3-PEG4-C2-NHS ester, CAS 944251-24-5
    N3-PEG4-C2-NHS ester, CAS 944251-24-5
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    Sku MEXHY-130109-100
    Manufact. SkuHY-130109-100
    Packaging Unit100 mg
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  9. N3-PEG4-C2-Pfp ester, CAS 1353012-00-6
    N3-PEG4-C2-Pfp ester, CAS 1353012-00-6
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    Sku MEXHY-130108-50
    Manufact. SkuHY-130108-50
    Packaging Unit50 mg
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  10. N3-PEG4-C2-Pfp ester, CAS 1353012-00-6
    N3-PEG4-C2-Pfp ester, CAS 1353012-00-6
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    Sku MEXHY-130108-25
    Manufact. SkuHY-130108-25
    Packaging Unit25 mg
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