CloneID: VHH-1
Antigen Long Description: The original antibody was generated by immunizing alpacas with IgG1-Fc recombinant protein, creating the appropriate phage display library, and panning against the original target.
Buffer Composition: PBS only.
Chimeric Use Statement: This is a chimeric antibody, developed from the original camelid VHH antibody, specifically engineered for enhanced compatibility with existing reagents, assays, and techniques.
Uniprot Accession No.: P0DOX5
Specificity Statement: This antibody is specific for the Fc domain of human IgG1.
Application Notes (Clone): The specificity of the original camelid (alpaca) single-domain antibody (sdAb; VHH) for the Fc domain of human IgG1 was tested in an ELISA. A fluorescently conjugated version of the original antibody was generated and used for affinity detection and flow cytometry. An EC50 of 0.27 nM was reported (CN114181314B).
English
Deutsch
