CloneID: 2G9
Antigen Long Description: The original antibody was generated by immunizing New Zealand white rabbits with recombinant Mouse IL-6 protein (Uniprot ID:P08505).
Buffer Composition: PBS with 0.02% Proclin 300.
Available Custom Conjugation Options: AP, HRP, Fluorescein, APC, PE, Biotin Type A, Biotin Type B, Streptavidin, FluoroProbes 647H, Atto488, APC/Cy7, PE/Cy7
Uniprot Accession No.: P08505
Specificity Statement: This antibody binds mouse IL-6, a cytokine found in fibroblasts, monocytes/macrophages, T lymphocytes, B lymphocytes and a variety of tumor cells. IL-6 plays an important role in immune response, hematopoiesis, inflammation and stress response.
Application Notes (Clone): This antibody binds mouse IL-6 with a binding affinity in the nanomolar range. This antibody was used as a labelling antibody in combination with 12E1 as a capture antibody for the development of a sandwich ELISA assay for detection of mouse IL-6. This antibody pair specifically recognized mouse IL-6 in samples with a sensitivity as low as 1.56pg/mL (CN116715763).