CloneID: 1C5-F5
Antigen Long Description: The original antibody was generated by immunizing BLAB/c mice with SFTSV JS-2010-003 strain purified by β-propiolactone inactivation.
Buffer Composition: PBS only.
Uniprot Accession No.: A0A0B5A886
Specificity Statement: This antibody binds the severe fever and thrombocytopenic syndrome virus glycoprotein C. Severe Fever with Thrombocytopenia Syndrome (SFTS) is an emerging infectious disease caused by the SFTS virus which is transmitted to humans through the bite of an infected tick. Most patients have symptoms such as fever, low platelet count and leukopenia, and may also have symptoms such as nausea, vomiting, diarrhea, headache, muscle pain, lymphatic enlargement, and bleeding. Recently, first case of human-to-human transmission of SFTS virus was reported in Japan.
Application Notes (Clone): The binding of this antibody towards SFTSV glycoprotein C was confirmed using ELISA. A double antibody sandwich ELISA was developed using 1H6-B10 as a coating antibody and HRP conjugated 1C5-F5 as a detection antibody. The detection system can detect from virus culture supernatant down to a sensitivity of about 60ng/ml (CN108178796).
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