CloneID: B12
Antigen Long Description: This antibody was raised from a phage-displayed scFv antibody library
Buffer Composition: PBS with 0.02% Proclin 300.
Available Custom Conjugation Options: AP, HRP, Fluorescein, APC, PE, Biotin Type A, Biotin Type B, Streptavidin, FluoroProbes 647H, Atto488, APC/Cy7, PE/Cy7
Specificity Statement: This antibody is specific for misfolded SOD1.
Application Notes (Clone): This antibody was used for a western blot on reacted against denatured wt and mt SOD1. It reacted to denatured wt, A4V and G93A SOD1 proteins but not the control SH3 protein. This antibody was used in vitro on NSC cells to determine the effect of the antibody on A4V and G93A mtSOD1 mediated cell death. The antibody has shown the ability to decrease the cell death caused by A4V and G93A mtSOD1 (Ghadge et al., 2014; PMID:23607939).
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