CloneID: LY2062430 (Solanezumab, hu266)
Heavy Chain modification: Fc Silent™
Antigen Long Description: The parental mouse antibody 266 was generated by immunization of mice with a peptide composed of residues 13-28 of human Aβ peptide. The original humanized version of the antibody was generated by grafting CDRs of the mouse antibody onto human framework regions.
Buffer Composition: PBS only.
Concentration: 1 mg/ml
Chimeric Use Statement: This is a reformatted mouse IgG2b Fc Silent™ antibody, based on the original mouse IgG1 format, created for improved compatibility with existing reagents, assays and techniques.
Uniprot Accession No.: P05067