Anzurstobart, CAS 2543693-10-1

Product Description: Anzurstobart (CC-95251; BMS-986351) is a high-affinity, fully human monoclonal anti-SIRPα antibody that blocks the binding of CD47 to SIRPα. Anzurstobart enhances macrophage phagocytic activity against DLBCL cell lines in co-culture models when combined with the antibody Rituximab (HY-P9913). Anzurstobart has the potential for solid and hematologic malignancies research[1].

Applications: Cancer-programmed cell death

Formula: N/A

References: [1]Henry Chan, et al. Discovery and Preclinical Characterization of CC-95251, an Anti-SIRPα Antibody That Enhances Macrophage-Mediated Phagocytosis of Non-Hodgkin Lymphoma (NHL) Cells When Combined with Rituximab. Blood (2021) 138 (Supplement 1): 2271.

CAS Number: 2543693-10-1

Molecular Weight: N/A

Compound Purity: 95.91

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Others

• SKU: MEXHY-P990033-5
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-P990033-5
• Green Labware: No
• Package Unit: 5 mg
• Quantity Unit: STK