Ascrinvacumab, CAS 1463459-96-2

Product Description: Ascrinvacumab (PF-03446962) is a human IgG2 monoclonal antibody targets ALK-1. Ascrinvacumab shows binding efficiency with human ALK1 with a Kd value of 7 nM. Ascrinvacumab can be used for the research of hepatocellular carcinoma (HCC)[1].

Applications: Cancer-Kinase/protease

Formula: N/A

References: [1]van Meeteren LA, et al. Anti-human activin receptor-like kinase 1 (ALK1) antibody attenuates bone morphogenetic protein 9 (BMP9)-induced ALK1 signaling and interferes with endothelial cell sprouting. J Biol Chem. 2012 May 25;287(22):18551-61.

CAS Number: 1463459-96-2

Molecular Weight: N/A

Compound Purity: 97.45

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Anaplastic lymphoma kinase (ALK)

• SKU: MEXHY-P99353-1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-P99353-1
• Green Labware: No
• Package Unit: 1 mg
• Quantity Unit: STK