Product Description: Asfotase alfa (ENB-0040) is a bone-targeted genetically engineered glycoprotein. Asfotase alfa increases the survival rate, bone mineralization and bone length and prevents mineralization defects of the feet, rib cage, lower limbs, jaw bones in Akp2?/? knockout mice. Asfotase alfa can be used for the research of perinatal, infantile, and juvenile-onset hypophosphatasia (HPP)[1].
Applications: Metabolism-protein/nucleotide metabolism
Formula: N/A
References: [1]Yadav MC, et al. Dose response of bone-targeted enzyme replacement for murine hypophosphatasia. Bone. 2011 Aug;49(2):250-6.
CAS Number: 1174277-80-5
Molecular Weight: N/A
Compound Purity: 97.88
Research Area: Metabolic Disease
Solubility: 10 mM in DMSO
Target: Phosphatase