Canakinumab, CAS 914613-48-2

Product Description: Canakinumab (ACZ885) is a recombinant human anti-IL-1β monoclonal antibody. Canakinumab shows IC50 values of 43.6 and 40.8 pM for human and marmoset IL-1β, respectively. The mode of action of canakinumab is based on the neutralization of IL-1β signaling, resulting in suppression of inflammation related to disorders of autoimmune origin[1][2].

Applications: COVID-19-immunoregulation

Formula: N/A

References: [1]Dhimolea E. Canakinumab. MAbs. Epub 2010 Jan 15. /[2]Rondeau JM, et al. The molecular mode of action and species specificity of canakinumab, a human monoclonal antibody neutralizing IL-1β. MAbs. 2015;7(6):1151-60.

CAS Number: 914613-48-2

Molecular Weight: N/A

Compound Purity: 99.64

Research Area: Inflammation/Immunology

Solubility: 10 mM in DMSO

Target: Interleukin Related

• SKU: MEXHY-108810-5
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-108810-5
• Green Labware: No
• Package Unit: 5 mg
• Quantity Unit: STK