Carotuximab, CAS 1268714-50-6

Product Description: Carotuximab (TRC105) is a IgG1 monoclonal antibody that blocks endoglin (CD105) and its downstream Smad signaling pathway. Carotuximab has immunomodulatory and antineoplastic actions[1][2].

Applications: Cancer-Kinase/protease

Formula: N/A

References: [1]Katarina Tripska , et al. Monoclonal anti-endoglin antibody TRC105 (carotuximab) prevents hypercholesterolemia and hyperglycemia-induced endothelial dysfunction in human aortic endothelial cells. Front Med (Lausanne). 2022 Sep 7;9:845918./[2]June Baik, et al. Therapeutic effect of TRC105 and decitabine combination in AML xenografts. Heliyon. 2020 Oct 13;6(10):e05242.

CAS Number: 1268714-50-6

Molecular Weight: N/A

Compound Purity: 95.0

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: TGF-beta/Smad

• SKU: MEXHY-P99494-5
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-P99494-5
• Package Unit: 5 mg
• Quantity Unit: STK
• Conjugate: Unconjugated