Cosibelimab, CAS 2216751-26-5

Product Description: Cosibelimab (CK-301; TG-1501) is a high-affinity, fully human PD-L1-blocking monoclonal antibody that binds PD-L1 and blocks its interaction with PD-1. Cosibelimab has a functional Fc domain and is capable of inducing ADCC and complement-dependent cytotoxicity (CDC)-mediated killing of PD-L1+ cell lines, including lymphoma cells[1].

Applications: Cancer-programmed cell death

Formula: N/A

References: [1]Akintunde Akinleye, et al. Immune checkpoint inhibitors of PD-L1 as cancer therapeutics. J Hematol Oncol. 2019 Sep 5;12(1):92. 

CAS Number: 2216751-26-5

Molecular Weight: N/A

Compound Purity: 99.90

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: PD-1/PD-L1

• SKU: MEXHY-P99833-1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-P99833-1
• Package Unit: 1 mg
• Quantity Unit: STK
• Conjugate: Unconjugated