Crotedumab, CAS 1452387-69-7

Product Description: Crotedumab (REGN1193) is a fully human IgG4 monoclonal antibody that binds and inhibits glucagon receptor (GCGR), with a KD of 0.1 nM. Crotedumab can be used for the research of diabetes[1][2].

Applications: Metabolism-sugar/lipid metabolism

Formula: N/A

References: [1]Kostic A, et, al. A first-in-human pharmacodynamic and pharmacokinetic study of a fully human anti-glucagon receptor monoclonal antibody in normal healthy volunteers. Diabetes Obes Metab. 2018 Feb;20(2):283-291. /[2]Okamot H, et, al. Glucagon Receptor Blockade With a Human Antibody Normalizes Blood Glucose in Diabetic Mice and Monkeys. Endocrinology. 2015 Aug;156(8):2781-94.

CAS Number: 1452387-69-7

Molecular Weight: N/A

Compound Purity: 96.61

Research Area: Metabolic Disease

Solubility: H2O

Target: GCGR

• SKU: MEXHY-P99357-1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-P99357-1
• Green Labware: No
• Package Unit: 1 mg
• Quantity Unit: STK