Product Description: CTX-471 is a fully human monoclonal antibody of CD137. CTX-471 has bind affinity for recombinant human, cynomolgus macaque CD137 and mouse CD137 with Kd values of 50 nM, 61 nM and 748 nM, respectively. CTX-471 can be used for the research of immunomodulation and cancer[1].
Applications: COVID-19-immunoregulation
Formula: N/A
References: [1]Ugur Eskiocak, et al. Differentiated agonistic antibody targeting CD137 eradicates large tumors without hepatotoxicity. JCI Insight. 2020 Mar 12;5(5):e133647.
CAS Number: 2377152-49-1
Molecular Weight: N/A
Compound Purity: 99.42
Research Area: Cancer; Inflammation/Immunology
Solubility: 10 mM in DMSO
Target: Interleukin Related