Denosumab (anti-TNFSF11), CAS 615258-40-7

Product Description: Denosumab (anti-TNFSF11) is a RANKL inhibitor that is effective against giant cell tumor of bone (GCTB).Denosumab eliminates RANK-positive tumor giant cells and reduces the relative content of proliferative, dense-cell tumor stromal cells[1].

Applications: Cancer-programmed cell death

Formula: N/A

References: [1]Branstetter DG, et al. Denosumab induces tumor reduction and bone formation in patients with giant-cell tumor of bone. Clin Cancer Res. 2012 Aug 15;18(16):4415-24.

CAS Number: 615258-40-7

Molecular Weight: N/A

Compound Purity: 95.00

Research Area: cancer

Solubility: 10 mM in DMSO

Target: RANKL/RANK

• SKU: MEXHY-P9958A-1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-P9958A-1
• Package Unit: 1 mg
• Quantity Unit: STK
• Conjugate: Unconjugated