Eciskafusp alfa, CAS 2649758-52-9

Product Description: Eciskafusp alfa is a programmed cell death 1 (PDCD1, best known as PD-1) cis-targeted IL2v immunocytokine. Eciskafusp alfa preferentially targets antigen-specific stem-like PD-1+ TCF-1+ CD8+ T cells and differentiates them towards a novel population of better effectors. Eciskafusp alfa can be used for the research of cancer and chronic infections[1].

Applications: COVID-19-immunoregulation

Formula: N/A

References: [1]Codarri Deak L, et al. Beyond checkpoint inhibition: PD-1 cis-targeting of an IL-2Rβγ-biased interleukin-2 variant as a novel approach to build on checkpoint inhibition. Oncoimmunology. 2023 Mar 30;12(1):2197360.

CAS Number: 2649758-52-9

Molecular Weight: N/A

Research Area: Cancer; Infection

Solubility: H2O

Target: PD-1/PD-L1

• SKU: MEXHY-P990029-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-P990029-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK