Eldelumab, CAS 946414-98-8

Product Description: Eldelumab (BMS-936557) is a human anti-CXCL10 (IP-10) monoclonal antibody (IgG1 type). Eldelumab selectively binds to CXCL10 and blocks CXCL10-induced calcium flux and cell migration. Eldelumab can be used in studies of autoimmune and auto-inflammatory diseases such as rheumatoid arthritis, ulcerative colitis and crohn's disease[1][2].

Applications: COVID-19-immunoregulation

Formula: N/A

References: [1]Gupta RK, et al. Drug repurposing for COVID-19 based on an integrative meta-analysis of SARS-CoV-2 induced gene signature in human airway epithelium. PLoS One. 2021 Sep 28;16(9):e0257784. /[2]Asquith DL, et al. Targeting cell migration in rheumatoid arthritis. Curr Opin Rheumatol. 2015 Mar;27(2):204-11.

CAS Number: 946414-98-8

Molecular Weight: N/A

Compound Purity: 95.00

Research Area: Inflammation/Immunology

Solubility: 10 mM in DMSO

Target: CXCR

• SKU: MEXHY-P99190-10
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-P99190-10
• Green Labware: No
• Package Unit: 10 mg
• Quantity Unit: STK